Product Info Summary
SKU: | A02556 |
---|---|
Size: | 100 µl |
Reactive Species: | Human, Rat |
Host: | Rabbit |
Application: | IF, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-BAF250B ARID1B Antibody
SKU/Catalog Number
A02556
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-BAF250B ARID1B Antibody (Catalog # A02556). Tested in WB, IF applications. This antibody reacts with Human, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-BAF250B ARID1B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02556)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from interal of human BAF250B.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02556 is reactive to ARID1B in Human, Rat
Applications
A02556 is guaranteed for IF, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
236.123kDa
Background of ARID1B
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth By similarity. Binds DNA non-specifically.
Mungall A.J., Nature 425:805-811(2003).
Mangel L., J. Biol. Chem. 273:30466-30471(1998).
Imbert G., Nat. Genet. 14:285-291(1996).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
Submit A Review
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1:500~1:3000
Immunofluorescence: 1:100~1:500
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of extracts from LOVO cells, using BAF250B antibody A02556.
Click image to see more details
Immunofluorescence analysis of HUVEC cells, using BAF250B antibody A02556.
Protein Target Info & Infographic
Gene/Protein Information For ARID1B (Source: Uniprot.org, NCBI)
Gene Name
ARID1B
Full Name
AT-rich interactive domain-containing protein 1B
Weight
236.123kDa
Alternative Names
6A3-5; ARID domain-containing protein 1B; AT rich interactive domain 1B (SWI1-like); BAF250B; BRG1-associated factor 250b; BRG1-binding protein ELD/OSA1; BRG1-binding protein hELD/OSA1; BRIGHT; DAN15P250R; ELD (eyelid)/OSA protein; ELD/OSA1; hOsa2; JPUT1; KDM5B; KIAA1235AT-rich interactive domain-containing protein 1B; Osa homolog 2; OSA2; p250R; PLU1; RBBP2H1A ARID1B 6A3-5, BAF250B, BRIGHT, CSS1, DAN15, ELD/OSA1, MRD12, OSA2, P250R AT-rich interaction domain 1B AT-rich interactive domain-containing protein 1B|ARID domain-containing protein 1B|AT rich interactive domain 1B (SWI1-like)|BRG1-associated factor 250b|BRG1-binding protein ELD/OSA1|ELD (eyelid)/OSA protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ARID1B, check out the ARID1B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ARID1B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-BAF250B ARID1B Antibody (A02556)
Hello CJ!
No publications found for A02556
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-BAF250B ARID1B Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
Be the first to review Anti-BAF250B ARID1B Antibody
*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question